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Trump Targets Prescription Costs With Huge TrumpRx Expansion

President Trump announced Monday that his administration is dramatically expanding its TrumpRx prescription drug platform, adding more than 600 generic medications while receiving an unexpected endorsement from billionaire entrepreneur Mark Cuban.

The expansion increases the number of available drugs by nearly sevenfold and marks a major shift from the platform’s initial February launch, which debuted with just 43 branded prescription medications.

“We’re increasing the number of drugs available on TrumpRx by nearly seven times,” Trump said during the announcement, arguing that generic medications can provide patients with the same treatments at a fraction of the cost.

The website now features two categories: “Presidential Deals” for branded medications and “Standard Prices” for generic drugs. Many of the branded drugs listed already have generic alternatives available.

Cuban — founder of Cost Plus Drugs, a company built around lowering prescription costs — praised the initiative and framed lower drug prices as one of the few issues capable of cutting across political lines.

“Republicans want cheaper drugs, independents want cheaper drugs, Democrats want cheaper drugs,” Cuban said. “Together I think we’re going to do something special.”

The public show of support is notable given Cuban’s own involvement in the prescription drug industry. He previously wrote on social media that “anything that saves patients money is a win.”

Questions remain over how much of an impact the program will have on insured patients. Analysts raised concerns when TrumpRx first launched, arguing that many Americans with prescription coverage may see limited savings. However, certain medications — including some fertility and weight-loss drugs — often face coverage gaps or high out-of-pocket costs.

Administration officials argue the effort is aimed at a broader affordability problem affecting millions of Americans.

“This administration and president’s leadership [is] making life more affordable,” said Mehmet Oz, who pointed to data showing many Americans struggle to fill prescriptions because of cost.